Stochastic Processes at Single-Molecule and Single-Cell Levels
Prof. Hao Ge
Beijing International Center for Mathematical Research
Due to the advance of single-molecule techniques, stochastic phenomena in chemistry and biology have been widely observed, which promotes the rapid development of stochastic modeling. I will discuss several stochastic processes in single-molecule enzyme kinetics, transcriptional burst and toggle switch. The stochastic modeling not only can explain some unexpected law from the trajectory perspective, but also can help uncover certain molecular mechanism and carefully analyze the effect of noise within gene regulation.