Viscoelastic Lipid Bilayers: Theory and Applications

Prof. Padmini Rangamani
Department of Mechanical and Aerospace Engineering
UC San Diego


The theory of intra-surface viscous flow on lipid bilayers is developed by combining the equations for flow on a curved surface with those that describe the elastic resistance of the bilayer to flexure. The model is derived directly from balance laws and augments an alternative formulation based on a variational principle. Conditions holding along an edge of the membrane are emphasized and the coupling between flow and membrane shape is simulated numerically. Particular applications that will be discussed in this talk include lipid flow on minimal surfaces, osmotic pressure drive membrane deformation, and ow due to protein adsorption.

Brief Bio. Padmini Rangamani is an assistant professor in Mechanical Engineering at the University of California, San Diego. She joined the department in July 2014. Earlier, she was a UC Berkeley Chancellors Postdoctoral Fellow, where she worked on lipid bilayer mechanics. She obtained her Ph.D. in biological sciences from the Icahn School of Medicine at Mount Sinai. She received her B.S. and M.S. in Chemical Engineering from Osmania University (Hyderabad, India) and Georgia Institute of Technology respectively. She is the recipient of the Air Force Office of Scientific Research Young Investigator Award for 2015.