Math 288 C00
Winter 2010

Time and place:  Thursdays 2:00-2:50pm, AP&M 5402 (except for the week of Feb.9 when it’ll be on Tuesday 11-11:50am, same room)

                               ********** Announcements ************

 

·       This biostatistics seminar continues next quarter, please sign up if you are interested.

·        See references 7-9 for week 9 talk by Dr.Deutsch.

 

                               ********** Schedule ************

 

·       Week 1: organizational, Introduction to Biostatistics (Xu).

·       Week 2: clinical trials (sequential, phase III) (Haut)

·       Week 3: observational studies (propensity score, instrumental variables) (Garner)

·       Week 4: high-dimensional data (chapter 3 in book below) (Chan)

·       Week 5: longitudinal data (Faig)

·       Week 6 (Tues 2/9 11am): Dr. Natarajan (UCSD SOM)

·       Week 7: Dr. Donohue (UCSD SOM)

·       Week 8: on missing data (Dr.Ard, SOM)

·       Week 9: Dr. Deutsch (UCSD SOM)

·       Week 10: Dr. Shen (Amylin Pharmaceutical)

 

 

 

 

References:

1.    Cnaan, A., Laird, N.M. and Slasor, P. (1997) Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data. Statistics in Medicine, 16, 2349-2380.

2.    Li and Xu (eds, 2008). High-Dimensional Data Analysis in Cancer Research. Springer.

3.    Sylvester et al. (2002) Statistical methodology of phase III cancer clinical trials: advances and future perspectives. European Journal of Cancer, 38, S162-168.

4.    Jennison and Turnbull (1990). Statistical approaches to interim monitoring of medical trials: a review and commentary. Statistical Science, 5(3), 299-317.

5.    Angrist, Imbens and Rubin (1996). Identification of causal effects using instrumental variables. Journal of the American Statistical Association, 91, 444-455.

6.    D’Agostino RB, Jr. (1998) Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Statistics in Medicine, 17, 2265-2281.

7.   Dohil et al (June 2006). Understanding intestinal cysteamine bitartrate absorption.  Journal of Pediatrics, 764-769.

8.   Marcotte, Deutsch et al (2003). Prediction of incident neurocognitive impairment by plasma HIV RNA and CD4 levels early after HIV seroconversion. Arch Neurol, 60, 1406-1412.

9.   Deutsch R, Mindt MR, Xu R, Cherner M, Grant I, and the HNRC Group. Quantifying relative superiority among many binary-valued diagnostic tests in the presence of a gold standard. Journal of Data Science, 2009; 7(2): 161-177.